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The chemagic PCR Pure Kit is designed to purify PCR products by removing impurities while maintaining a high yield of PCR product. The protocol is scalable for purification from starting volumes less than 50 μl up to a few millilitres of PCR samples. PCR products larger than 100 bp in size have been purified. The purified PCR fragments are eluted in either a low salt buffer or water and can be used for microarrays, automated fluorescent DNA sequencing and restriction digestion.