ActipixD100 Area Imaging System I The ActiPix™ Nano-Sizing System I Teknologi I Produktspecifikationer I Tilbehør

ActiPix™ SDI300 Surface Dissolution Imager				MD Scientific er eneforhandler i Danmark for Paraytec
"A new tool that can reduce the time it takes to get a drug to market".				Catalogues and application notes

The ActiPix™ SDI300 is the world's first Surface Dissolution Imaging System. For the first time scientists can now directly image surface dissolution processes to enable a better mechanistic of dissolution processes. Intrinsic dissolution rate (IDR) measurements can be obtained in <20 minutes. The system is ideal for liquids, gels and powders for use in development and formulations laboratories. The ActiPix Dissolution Imager is a powerful new tool for analysing convective diffusion and drug dissolution. Flow-through system with well-defined laminar flow characteristics and established theory. High spatial resolution allows quantitative studies of the API over the key distance scale 0 – 1000 microns from the surface. Short time to steady state (120 s) allows study of effects of flow rate change in one experimental run. The pharmaceutical industry is looking for a number of ways to: Streamline its drug development process Test the quality of its formulations Test generics to see if they are infringing patents Generic companies are looking for fast methods of copying out of patent formulations Reduce the time it takes a drug to come to market

• Actipic SDI300 Surface Dissolution Imager - leaflet (pdf)
• An introduction to surface dissolution imaging (pdf)
• ActiPix™ SDI300 Dissolution Imager product note (pdf)
• Surface Dissolution Imaging: A powerful new tool for formulations optimization (pdf)

The ActiPix™ SDI300 Dissolution Imager utilises Paraytec’s award-winning patented ActiPix™ technology. It contains a 9 mm x 7 mm UV imaging sensor, with up to 1.3 million 7 µm  pixels used to record, interrogate and analyse a variety of complex processes. The wavelength can be selected to allow high sensitivity monitoring of the substance of interest. It is the first tool of its kind to offer accurate, quantitative and mechanistic information for a variety of applications.

It can be used as a flexible, multi-purpose tool for accelerated pre-formulations development. Intrinsic dissolution rates can be obtained in less than 20 minutes, i.e. a fraction of the time compared to conventional systems. It could also be used to image the release of an active pharmaceutical ingredient from a variety of sample types, i.e. powders, liquids and gels. 

The ActiPix™ SDI300 Dissolution Imager can be used for other applications such as monitoring the rate of diffusion of species through membranes as well as to provide fundamental information of amorphous to crystalline transformations. The ActiPix™ SDI300 Dissolution Imager can be placed in a temperature controlled environment, for example to simulate physiological conditions.

Accessories and Cartridges

---

ActiPix™ TDA200 HT Nano-Sizing System

ActiPix™ D100 UV Area Imaging System

---

 

MD Scientific ApS • Denmark • tlf. 7027 8565 • fax 7027 8566 • info@md-scientific.dk