Hypersil Gold kolonner/columns

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MD Scientific er autoriseret forhandler i Danmark af kolonner og tilbehør for Thermo Scientific

Hypersil GOLD™ Columns: Unlock your HPLC Potential with Outstanding Peak Shape		Oversigt over alle Thermo-kolonner
1.9 µm Hypersil GOLD Columns Hypersil GOLD C8 Columns Hypersil GOLD CN Columns Hypersil GOLD Capillary Columns Hypersil GOLD Columns Hypersil GOLD PFP Columns Hypersil GOLD Phenyl Columns Hypersil GOLD aQ™ Columns

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1.9 µm Hypersil GOLD Columns

1.9 µm Hypersil GOLD is available in C18, PFP and aQ (polar embedded C18) selectivities offering you a number of retention options.

Hypersil GOLD C8 Columns

Hypersil GOLD C8 columns offer outstanding peak shape and performance with less retention than the original Hypersil GOLD.

Based upon the same highly pure silica as the original Hypersil GOLD C18 columns, Hypersil GOLD C8 columns also provide very symmetrical peak shapes while also improving capabilities such as speed of analysis, efficiency and sensitivity. Hypersil GOLD C8 media provides similar selectivity to C18 with a predictable elution order, but less retention.  This will be of particular interest when trying to analyze compounds in a shorter amount of time, or where smaller amounts of hydrophobicity are needed in order to successfully retain compounds of interest.

Speed of Analysis

Hypersil GOLD C8 provides improved throughput of analysis over that of a C18 alkyl chain chemistry.  Hydrophobicity interactions are reduced, allowing compounds to elute quicker from the column.  Where simple analyte mixtures are being analyzed, suitable resolution will still be achieved.

Hypersil GOLD CN Columns

Cyano columns based on high purity silica for excellent peak shape in reversed phase and normal phase separations.

Hypersil GOLD CN are based on the highly pure Hypersil GOLD silica, offering excellent peak shapes while also providing complementary selectivity in reversed phase chromatography with lower hydrophobicity compared to alkyl chain phases.  Hypersil GOLD CN columns can also be used in normal phase chromatography, where they offer less retention and different selectivity compared to silica columns. The Hypersil GOLD silica and bonding techniques improve capabilities such as speed of analysis, peak shape and sensitivity over other CN phases.  This will be of particular interest when trying to analyze compounds very quickly or when selectivity enhancements are needed.

Selectivity

Hypersil GOLD CN columns help to extend the range of selectivities available.  It is applicable in both reversed phase and normal phase chromatography and offers alternative selectivity in both modes.  A wide range of compounds can be analyzed using Hypersil GOLD CN, from steroids in reversed phase to sugars and other polar entities in normal phase, allowing confirmational results to be achieved.

Hypersil GOLD Capillary Columns

• KAPPA capillary columns in 75 to 500µm ID  
• Exceptional peak symmetry and resolution
• Enhanced sensitivity 
• Ideal first choice for new method development

Hypersil GOLD columns are a new LC and LC/MS column offering excellent peak shape. Based on highly pure silica, Hypersil GOLD columns provide outstanding symmetrical peaks, even when analyzing compounds that give notoriously poor peak shape on traditional C18 or L1 chemistries.

Rugged and robust manufacturing processes coupled with advanced column packing technologies produce highly efficient, reliable Hypersil GOLD columns for applications where resolution between compounds closely related in structure is paramount. Discrimination between such species is vital in drug analyses where active constituents and other trace components must be rigorously monitored. With L1 retention and selectivity, existing L1 methodologies are easily upgraded to Hypersil GOLD columns with minimal loss of time, but with an improvement in peak shape and sensitivity.

The 5µm material is available in high efficiency KAPPA capillary columns, optimizing performance and sensitivity.  These columns are ideal for LC/MS applications, especially where sample size is limited.  They are available in 500, 320, 180, 100 and 75µm ID capillaries in lengths or 50, 100, 150 and 250 mm.  30mm guard columns are available in 500, 320 and 180µm ID to protect your analytical column.

Hypersil GOLD Columns

• Exceptional peak symmetry and resolution
• Based on next-generation ultra pure silica
• Outstanding pH stability
• Ideal first choice for new method development

Hypersil GOLD columns are a new LC and LC/MS column offering excellent peak shape. Based on highly pure silica, Hypersil GOLD columns provide symmetrical peaks, even when analyzing compounds that give notoriously poor peak shape on traditional C18 or L1 chemistries.

Rugged and robust manufacturing processes coupled with advanced column packing technologies produce highly efficient, reliable Hypersil GOLD columns for applications where resolution between compounds closely related in structure is paramount. Discrimination between such species is vital in drug analyses where active constituents and other trace components must be rigorously monitored. With L1 retention and selectivity, existing L1 methodologies are easily upgraded to Hypersil GOLD columns with minimal loss of time, but with an impressive gain in peak shape and sensitivity.

The 3µm and 5µm Hypersil GOLD columns are available in both unique and conventional formats, including standard analytical columns, KAPPA capillary columns, DASH high-throughput LC/MS columns, as well as several guard formats. Analytical columns and capillaries range in dimension from 75µm to 4.6mm ID and lengths from 20 to 250mm. For preparative work, Hypersil GOLD is also available in 8µm particle size and larger column dimensions, allowing ultimate flexibility in method development and transfer.

Hypersil GOLD PFP Columns

Outstanding performance and unique selectivity with Hypersil GOLD perfluorinated columns.

Hypersil GOLD PFP (perfluorophenyl) columns build on the performance of the Hypersil GOLD columns by providing excellent peak shapes while also offering alternative selectivity in reversed phase chromatography compared to alkyl chain phases.  The Hypersil GOLD manufacturing process provides improvements in speed of analysis, peak shape and sensitivity over other fluorinated phases.  This will be of particular interest when trying to analyze compounds which are difficult to retain or which have complex halogenated functionality.

Unique Selectivity

Hypersil GOLD PFP columns help to extend the range of selectivities that are provided in reversed phase chromatography.  This phase will increase retention and resolution, and is particularly suited to separation of halogenated species as well as compounds containing hydroxyl, carboxyl, nitro or other polar groups.  The additional mechanisms of the PFP phase, such as steric selectivity of the analyte species and dipole interactions, offer alternative selectivity.  Perfluorinated phases like Hypersil GOLD PFP are frequently used in the analysis of complex taxane samples.

Hypersil GOLD Phenyl Columns

• Alternative selectivity for aromatic and moderately polar analytes
• Pi-pi interactions with aromatics
• Moderate hydrophobicity
• Outstanding peak shape and sensitivity

Hypersil GOLD™ phenyl reversed phase columns exhibit alternative selectivity to alkyl chain columns, particularly for aromatic and moderately polar analytes. The Hypersil GOLD phenyl bonded phase contains a butyl linker which allows for superior alignment of the phenyl ring with aromatic molecules, enhancing pi-pi interactions and therefore retention. The C4 linker also provides the stationary phase with moderate hydrophobicity, making it ideal for the separation of analyte mixtures with varying polarity and aromaticity.

Because Hypersil GOLD phenyl columns are based upon the high purity Hypersil GOLD silica, outstanding peak shape and sensitivity is assured. Hypersil GOLD phenyl columns are available with particle sizes from 1.9 to 5 μm.

Hypersil GOLD aQ™ Columns

• Retention and resolution of polar analytes
• Ideal for highly aqueous mobile phases
• Polar endcapped C18 phase for alternative selectivity
• Excellent peak shapes
• Also available in 1.9 μm particle size

Hypersil GOLD aQ™ is built upon the technology of the Hypersil GOLD™ silica, ensuring optimized peak shape, and therefore, resolution, sensitivity and efficiency. Because Hypersil GOLD aQ is a polar endcapped C18 phase, it also offers superior retention of polar compounds. Dispersive interactions are the primary mechanism of retention with alkyl chain bonded phases. The polar functional group used to endcap Hypersil GOLD aQ provides an additional interaction mechanism by which polar compounds can be retained and resolved. This additional interaction mechanism may often provide selectivity differences over the traditional alkyl chain chemistries, and offers a solution for the separation of polar compounds which exhibit insufficient retention on pure alkyl chain phases under typical reversed phase mobile phase conditions.

For flere detaljer og pris, kontakt venligst MD Scientific via e-mail: info@md-scientific.dk eller telefon: 7027 8565.

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